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Biology · Cell Biology

Microscope Magnification

Multiply the objective lens by the eyepiece to get the total magnification of a compound microscope.

Objective lensThe lens on the rotating turret nearest the specimen.
The lens you look through — usually 10×.
Common objectives — tap to load
Total magnification
400×

40× objective × 10× eyepiece = 400× total

Total magnification on a compound microscope is the objective lens magnification multiplied by the eyepiece (ocular) magnification. With the common high-power 40× objective and a standard 10× eyepiece, the total is 40× × 10× = 400×. Swap in the 100× oil-immersion objective and the same eyepiece gives 1000×.

How total magnification works

A compound light microscope magnifies in two stages. The objective lens — mounted on the rotating turret just above the specimen — produces a first magnified image, and the eyepiece (the ocular lens you look through) magnifies that image again. Because the two lenses act in series, their powers multiply rather than add. The eyepiece is almost always 10×, so the total scales directly with whichever objective you rotate into place: 4×, 10×, 40×, or 100×.

total magnification = objective × eyepiece

Both lenses act in series, so their magnifications multiply.

Worked example: 40× objective, 10× eyepiece

Find the total magnification when viewing a cheek-cell slide under high power:

  1. 1
    Read the objective lens. The high-power dry objective is engraved 40×.
  2. 2
    Read the eyepiece. The ocular lens is marked 10×, the standard value.
  3. 3
    Multiply the two. 40× × 10× — the lenses act in series, so multiply rather than add.
  4. 4
    Read off the total. 40 × 10 = 400, so the specimen is magnified 400× overall.

Total magnification by objective (with a 10× eyepiece)

Standard objective powers on a compound microscope, each paired with the usual 10× ocular.

ObjectiveEyepieceTotalTypical use
10×40×Scanning — locate the specimen
10×10×100×Low power — survey the field
40×10×400×High power (dry) — cells in detail
100×10×1000×Oil immersion — bacteria, fine structure

Magnification, resolution, and the shrinking field

Magnification is not resolution. Magnification only enlarges the image; resolution is the smallest distance at which two points stay separate. Past the useful limit, more magnification just produces a bigger, blurrier picture — “empty magnification.” The objective’s numerical aperture, not its power, sets how much real detail you can resolve.

Higher power narrows the field of view. As total magnification rises, the visible circle shrinks in proportion: the field-of-view diameter at high power equals the low-power diameter times the ratio of the magnifications. Going from 100× to 400× (a 4× jump) shrinks the field to a quarter of its width, so you see less of the slide and must re-centre your specimen before switching up.

The 100× objective needs oil. The 100× oil-immersion lens is used with a drop of immersion oil between the lens and the coverslip. The oil’s refractive index matches the glass, bending more light into the lens, raising the numerical aperture and giving the sharp, high-resolution image needed at 1000×.

What’s the difference between the objective and the eyepiece?
The objective is the lens on the turret closest to the specimen and does the first stage of magnification (4×, 10×, 40×, or 100×). The eyepiece, or ocular, is the lens you look through — usually 10×. Their powers multiply to give the total.
How do I calculate total magnification?
Multiply the objective magnification by the eyepiece magnification. A 40× objective with a 10× eyepiece gives 40 × 10 = 400× total.
Is magnification the same as resolution?
No. Magnification enlarges the image, while resolution is the smallest detail you can still distinguish. Beyond the resolution limit, extra magnification gives a larger but blurrier image — known as empty magnification.
Why does the field of view shrink at higher power?
The visible circle scales inversely with magnification: the high-power field diameter equals the low-power diameter times the ratio of the lower magnification to the higher one. Quadrupling the power cuts the field width to a quarter, so you see less of the slide.
What is the 100× oil-immersion objective?
It is the highest-power objective, used with a drop of immersion oil between the lens and the coverslip. The oil matches the refractive index of glass, raising the numerical aperture so the 1000× image stays sharp and detailed.
Does the eyepiece always have to be 10×?
Most compound microscopes ship with a 10× eyepiece, but some use 5×, 15×, or 20×. Whatever it is, multiply it by the objective — a 15× eyepiece with a 40× objective gives 600×.